Myogenin expression is independent of agrin treatment in C2C12 cell culture
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چکیده
منابع مشابه
C2C12 Cell Line is a Good Model to Explore the Effects of Herbal Extracts on GLUT4 Expression and Translocation
Objective: GLUT4 is a type of glucose transporter and plays a central role in whole-body metabolism of carbohydrates. The muscle is the major site of GLUT4 and cell line models, to explore GLUT4 behaviors under new therapeutic approach, such as herbal components, should be evaluated. Here, C2C12 cell line is evaluated for GLUT4 translocation from intracellular compartment into the cell membrane...
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Myogenin gene (MYoG) affects the synthesis of muscle myofibrillar growth and increase of meat production. The myostatin (MSTN) gene is identified as a specific negative regulator of skeletal muscle growth. Reduction of the expression level of MSTN throughmutation in the sequence of this gene leads to an increase of myogenesis and regeneration of muscle cells during the postnatal growing period ...
متن کاملc2c12 cell line is a good model to explore the effects of herbal extracts on glut4 expression and translocation
objective: glut4 is a type of glucose transporter and plays a central role in whole-body metabolism of carbohydrates. the muscle is the major site of glut4 and cell line models, to explore glut4 behaviors under new therapeutic approach, such as herbal components, should be evaluated. here, c2c12 cell line is evaluated for glut4 translocation from intracellular compartment into the cell membrane...
متن کاملexpression of glucose transporter 4 (glut4) is increased by cinnamaldehyde in c2c12 mouse muscle cells
background: in diabetes mellitus because of the absence or insufficient sensitivity to insulin, glucose transporter protein in cell membrane, glucose transporter 4, is decreased. glut4 is the major glucose transporter in skeletal muscle and adipose tissue, which is under control of insulin. it remains, however, unclear whether cinnamaldehyde plays a regulatory role(s) or not. objectives: the ob...
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The accumulation of two myogenic regulatory proteins, MyoD and myogenin, was investigated by double-immunocytochemistry and correlated with myosin heavy chain expression in different classes of myoblasts in culture and during early myogenesis in vivo. During in vitro differentiation of fetal myoblasts, MyoD-positive cells were detected first, followed by the appearance of cells positive for bot...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2010
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.24.1_supplement.451.5